Evolution of acetylcholinesterase and butyrylcholinesterase in the vertebrates: an atypical butyrylcholinesterase from the Medaka Oryzias latipes.
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are thought to be the result 6310 GLADEWATER SHOW SADDLE of a gene duplication event early in vertebrate evolution.To learn more about the evolution of these enzymes, we expressed in vitro, characterized, and modeled a recombinant cholinesterase (ChE) from a teleost, the medaka Oryzias la